Anti-trypanosomal activity and DNA fingerprinting of fifteen Euphorbia species using ISSR and SCoT markers

Abstract Background Euphorbia is the largest genus in family Euphorbiaceae with a great biological and genetic diversity. The anti-trypanosomal activity of crude extract 15 species against Trypanosoma brucei was carried out. Furthermore, DNA fingerprinting tested using ISSR SCoT markers also investigated. Results revealed highest E. officinarum L. milli Des Moul. IC 50 values < 10 ?g/mL after 48- 72-h incubation. Moreover, assessment diversity among showed similar correlation coefficients 0.76–0.98 which classified into two main groups, one contained other 13 species. Conclusions Some exhibited significant growth inhibitory toward strain TC221. indicated suitability both for To our knowledge, this first detailed comparison performance targeted molecular (SCoT ISSR) on results guide future efficient use these analysis .